I-Adipotide/GT Peptide/Peptide Supplier

Incazelo

I-adipotide (adipate) iyisidakamizwa esisha esibonisa isithembiso emkhakheni wocwaningo lokukhuluphala.Umuthi ekuqaleni wadalwa njenge-ejenti yokwelapha umdlavuza eklanyelwe ukulambisa amangqamuzana omdlavuza egazini ukuze amise ukukhula kwawo.Isenzo somuthi ochitha amafutha siphakamisa ukuthi lesi sidakamizwa silambisa amangqamuzana anamafutha egazini, okuphoqa ukuthi afe futhi aphinde athathwe umzimba.Ukuhlolwa kokuqala kwenziwa kumagundane kwase kudluliselwa ezinkawini.Imiphumela yokuhlolwa kwamagundane ibonise ukwehla ngo-30% kwesisindo somzimba.Ngemva kwamasonto amane imijovo nsuku zonke kaI-Adipotidekulandelwa amasonto amane okungelakwelashwa, izinkawu eziyishumi ezikhuluphele ze-rhesus zesifazane zalahlekelwa isilinganiso sesisindo somzimba sazo esingu-11% futhi zehlisa amafutha azo ngo-39%.Okuningi kokulahlekelwa kwenzeke ngezikhathi zokungalashwa.

Imininingwane

Ukubukeka: Impushana emhlophe ukuya kokumhlophe

Ubumsulwa(HPLC):≥98.0%

Ukungcola Okukodwa:≤2.0%

Okuqukethwe kwe-Acetate(HPLC): 5.0%～12.0%

Okuqukethwe Amanzi (Karl Fischer):≤10.0%

Okuqukethwe kwe-Peptide:≥80.0%

Ukupakisha Nokuthumela: Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, kunembile ku-mg njengoba kudingeka.

Unga-oda Kanjani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda ku-inthanethi.Sicela ugcwalise ifomu le-oda ku-inthanethi.

3. Nikeza igama le-peptide, Inombolo ye-CAS noma ukulandelana, ukuhlanzeka nokuguqulwa uma kudingeka, ubuningi, njll. sizohlinzeka ngekhotheshini kungakapheli amahora ama-2.

4. Ukugcinwa kwe-oda ngenkontileka yokuthengisa esayiniwe ngokufanelekile kanye ne-NDA(isivumelwano esingadalulwanga) noma isivumelwano esiyimfihlo.

5. Sizoqhubeka nokubuyekeza inqubekelaphambili ye-oda ngesikhathi.

6. Ukulethwa kwe-Peptide nge-DHL, i-Fedex noma abanye, kanye ne-HPLC, MS, COA izohlinzekwa kanye nempahla.

7. Inqubomgomo yembuyiselo izolandelwa uma kukhona ukushayisana kwekhwalithi noma isevisi yethu.

8. Isevisi yangemuva kokuthengisa: Uma amakhasimende ethu enemibuzo mayelana ne-peptide yethu ngesikhathi sokuhlolwa, sicela ukhululeke ukusithinta futhi sizoyiphendula ngokushesha.

Yonke imikhiqizo yenkampani isetshenziselwa inhloso yocwaningo lwesayensi kuphela, yona'kwenqatshelwe ukusetshenziswa ngokuqondile yinoma yimuphi umuntu emzimbeni womuntu.

FAQ:

Ingabe ama-peptide aqukethe ama-Cys ancishisiwe ngaphambi kokuthunyelwa?

Uma i-peptide ingatholakali ukuthi ifakwe i-oxidized, ngokuvamile asinciphisi ama-Cys.Wonke ama-polypeptide atholakala emikhiqizweni engcolile ehlanjululwe futhi i-lyophilized ngaphansi kwezimo ze-pH2, okuthi okungenani ngokwezinga elithile ivimbele ukukhishwa kwe-Cys.Ama-Peptide aqukethe ama-Cys ahlanzwa ku-pH2 ngaphandle uma kunesizathu esithile sokuhlanza ku-pH6.8.Uma ukuhlanzwa kwenziwa ku-pH6.8, umkhiqizo ohlanziwe kufanele uphathwe nge-asidi ngokushesha ukuze uvimbele ukugcotshwa kwe-oxidation.Esinyathelweni sokugcina sokulawula ikhwalithi, kuma-peptide aqukethe ama-Cys, uma ubukhona besisindo samangqamuzana (2P+H) butholakala kumephu ye-MS, kukhombisa ukuthi i-dimer yenziwe.Uma ingekho inkinga nge-MS kanye ne-HPLC, sizoziphilisa ngokuqondile futhi sithumele izimpahla ngaphandle kokuqhubeka nokucutshungulwa.Kufanele kuqashelwe ukuthi ama-peptide aqukethe ama-Cys athola i-oxidation ehamba kancane ngokuhamba kwesikhathi, futhi izinga le-oxidation lincike ekulandeleni kwe-peptide nezimo zokugcinwa.

Unquma kanjani ukuthi i-peptide i-looped?

Sisebenzisa ukusabela kuka-Ellman ukuhlola ukuthi ukwakheka kweringi kuqediwe yini.Uma ukuhlolwa kuka-Ellman ku-positive (okuphuzi), ukusabela kwendandatho akuphelele.Uma imiphumela yokuhlolwa inegethivu (hhayi ephuzi), ukusabela kwendandatho sekuqediwe.Asinikezi ngombiko wokuhlaziya wokuhlonza ibhayisikili kumakhasimende ethu.Ngokuvamile, kuzoba nencazelo yemiphumela yokuhlolwa kuka-Ellman embikweni we-QC.

Ngidinga i-cyclic peptide, equkethe i-tryptophan, ingabe izokwenziwa i-oxidized?

I-oxidation ye-tryptophan iyinto evamile ku-peptide oxidation, futhi ama-peptide avame ukuqhutshwa ngamabhayisikili ngaphambi kokuhlanzwa.Uma i-oxidation ye-tryptophan yenzeka, isikhathi sokugcinwa kwe-peptide kukholomu ye-HPLC sizoshintsha, futhi i-oxidation ingasuswa ngokuhlanzwa.Ngaphezu kwalokho, ama-peptide ane-oxidized nawo angatholwa yi-MS.

Ingabe kuyadingeka ukubeka igebe phakathi kwe-peptide nodayi?

Uma uzonamathisela i-molecule enkulu (njengodayi) ku-peptide, kungcono kakhulu ukubeka isikhala phakathi kwe-peptide ne-ligand ukuze unciphise ukuphazamiseka kwesamukeli ngokugoqa i-peptide ngokwayo noma ngokugoqa inhlanganisela yayo.Abanye abazifuni izikhawu.Isibonelo, ekugoqeni amaprotheni, kungenzeka ukunquma ukuthi ukuqhelelana kangakanani isakhiwo esigoqayo se-amino acid ngokunamathisela udayi we-fluorescent endaweni ethile.

Uma ufuna ukwenza ukuguqulwa kwe-biotin kutheminali engu-N, ingabe udinga ukubeka igebe phakathi kwe-biotin nokulandelana kwe-peptide?

Inqubo evamile yokulebula ye-biotin esetshenziswa inkampani yethu ukunamathisela i-Ahx ochungechungeni lwe-peptide, ilandelwe yi-biotin.I-Ahx iyinhlanganisela yekhabhoni engu-6 esebenza njengesithiyo phakathi kwe-peptide ne-biotin.

Ungakwazi yini ukunikeza iseluleko mayelana nokwakhiwa kwama-peptide e-phosphorylated?

Njengoba ubude bukhula, ukusebenza kahle kokubophezela kuyehla kancane kancane kusuka ku-amino acid e-phosphorylated kuye phambili.Isiqondiso se-synthesis sisuka ku-C terminal kuya ku-N terminal.Kutuswa ukuthi izinsalela ngemva kwe-amino acid ene-phosphorylated akumele zidlule ku-10, okungukuthi, inani lezinsalela ze-amino acid ngaphambi kwe-amino acid eyi-phosphorylated esuka ku-N terminal kuya ku-C terminal akufanele idlule ku-10.

Kungani i-n-terminal acetylation kanye ne-C-terminal amidation?

Lezi zinguquko zivimbela i-peptide ukuthi ingcoliswe futhi ivumele i-pepamagagasi ukulingisa isimo sawo sangempela samaqembu e-alpha amino ne-carboxyl kuphrotheni engumzali.