I-Cecropin A /80451-04-3/GT Peptide/Peptide Supplier

Ulwazi oluyisisekelo:

I-PeptideName:I-Cecropin A /Cecropin A, ingulube

Ikhathalogi No:I-GT-P063

Ukulandelana:Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Glu-Lys-Val-Gly-Gln-Asn-Ile-Arg-Asp-Gly-Ile-Ile-Lys-Ala-Gly-Pro-Ala- I-Val-Ala-Val-Val-Gly-Gln-Ala-Thr-Gln-Ile-Ala-Lys-NH

Inombolo ye-CAS:80451-04-3         

I-Molecular Formula:I-C184H313N53O46

Isisindo se-Molecular:4003.84

Isigaba:  Ikhathalogi peptide,I-peptide yangokwezifiso, i-polypeptide synthesis


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

Cecropin A, I-37-amino acid linear polypeptide, yehlisa ukusebenza kwamaseli e-HL-60 ngendlela encike kumthamo (10-50μM).I-Cecropin A (30μM) ithuthukisa ukukhiqizwa kwe-ROS, ibangela amandla olwelwesi lwe-mitochondrial (Δψm) ukuwa, futhi ikhiqize izinguquko ze-morphological ku-chromatin yenuzi kumaseli we-HL-60.I-Cecropin A (30μM) kuphinde kwabangela i-apoptosis yakuqala futhi kwaholela ekufeni kweseli elizimele le-caspase kumaseli e-HL-60.I-Cecropin A yayiyi-cytotoxic kubhaktheriya e-Gram-negative, okuhlanganisa i-Acinetobacter baumannii (CCARM 12005, CCARM 12035, CCARM 12036, kanye ne-CCARM 12037) ene-inhibitory concentration (MIC) encane engu-0.5-1μM. Cecropin A (25μM) ivimbe kakhulu inkulumo ye-mTNF-α, i-mIL-1β kanye ne-mMIP-2 mRNA, futhi ivimbe kancane isisho se-mMIP-1 mRNA kumaseli angu-RAW264.7.I-Cecropin A (0.1, 0.25, 0.5, 1, 2.5, 5μM) iphinde yavimbela ukukhiqizwa kwe-NO futhi yehlisa i-mTNF-α amazinga e-cytokine kumaseli e-RAW264.7 avuselelwe yi-LPS, futhi abonise umsebenzi wokulwa nokuvuvukala.

Imininingwane

Ukubukeka: Impushana emhlophe ukuya kokumhlophe

Ubumsulwa(HPLC):98.0%

Ukungcola Okukodwa:2.0%

Okuqukethwe kwe-Acetate(HPLC): 5.0%12.0%

Okuqukethwe Amanzi (Karl Fischer):10.0%

Okuqukethwe kwe-Peptide:80.0%

Ukupakisha Nokuthumela: Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, kunembile ku-mg njengoba kudingeka.

Unga-oda Kanjani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda ku-inthanethi.Sicela ugcwalise ifomu le-oda ku-inthanethi.

3. Nikeza igama le-peptide, Inombolo ye-CAS noma ukulandelana, ukuhlanzeka nokuguqulwa uma kudingeka, ubuningi, njll. sizohlinzeka ngekhotheshini kungakapheli amahora ama-2.

4. Ukugcinwa kwe-oda ngenkontileka yokuthengisa esayiniwe ngokufanelekile kanye ne-NDA(isivumelwano esingadalulwanga) noma isivumelwano esiyimfihlo.

5. Sizoqhubeka nokubuyekeza inqubekelaphambili ye-oda ngesikhathi.

6. Ukulethwa kwe-Peptide nge-DHL, i-Fedex noma abanye, kanye ne-HPLC, MS, COA izohlinzekwa kanye nempahla.

7. Inqubomgomo yembuyiselo izolandelwa uma kukhona ukushayisana kwekhwalithi noma isevisi yethu.

8. Isevisi yangemuva kokuthengisa: Uma amakhasimende ethu enemibuzo mayelana ne-peptide yethu ngesikhathi sokuhlolwa, sicela ukhululeke ukusithinta futhi sizoyiphendula ngokushesha.

Yonke imikhiqizo yenkampani isetshenziselwa inhloso yocwaningo lwesayensi kuphela, yona'kwenqatshelwe ukusetshenziswa ngokuqondile yinoma yimuphi umuntu emzimbeni womuntu.

FAQ:

Yiziphi izincomo uma ngiqala ukusebenzisa ama-peptide?

Uma usulungele ukusetshenziswa, landela lezi zinyathelo ezingezansi ukuze uncibilikise ama-peptide ukuze ugcine ikhwalithi yawo.

1, ngaphambi kokuvula ibhodlela nokukala ingxenye ye-peptide, yishise ukuze ufinyelele izinga lokushisa legumbi, futhi isikhathi sokushisa sinconywa ukuthi sibe yihora elingu-1.

2. Kala ngokushesha inani elidingekayo endaweni ehlanzekile yangaphandle.

3. Gcina ama-peptide asele efrijini ngezansi -20, engeza ama-desiccant bese uwagcina esitsheni esingangenisi umoya.

Ngihlala phesheya, futhi kuzothatha izinsuku ezimbalwa ukudiliva kanye nemvume yamasiko.Ingabe lokhu kuzoluthinta ucwaningo lwami?

Uthola ama-peptide kumaphakheji wempuphu e-lyophilized, futhi ama-peptides ngokuvamile angagcinwa endaweni yokushisa ngaphandle kokulimala.Sicela umise futhi ugcine ngokushesha ngemva kokuthola.

Yiziphi izinkinga okufanele zinakwe ohlelweni lokugcina?

I-peptide oyitholile ihlanganiswe ngempushana e-lyophilized.Ama-peptide ane-hydrophilic, futhi ukumuncwa kwamanzi kuzonciphisa ukuzinza kwe-peptide futhi kunciphise okuqukethwe kwe-peptide.Sicela unake lokhu okulandelayo: okokuqala, ngama-desiccants, agcinwe endaweni eyomile.Okwesibili, uma wathola, sicela ngokushesha ufake efrijini -20ukugcina, ukuze kugcinwe ukuzinza okukhulu.Okwesithathu, gwema ukusetshenziswa kwesiqandisi esizenzakalelayo sesiqandisi.Ukushintsha komswakama kanye nezinga lokushisa kungathinta ukuzinza kwama-peptide.Okwesine, izinga lokushisa langaphandle ngesikhathi sokuthutha akuthinti ukufaneleka kanye nekhwalithi yama-peptide.

Ngiwagcina kanjani ama-peptide afriziwe lapho ngithola umkhiqizo?

Uma usuyitholile, kufanele uyigcine ngokushesha ku -20° C noma ngaphansi.

Uma okuqukethwe kwe-peptide kungu-80%, yimuphi omunye u-20%?

Usawoti namanzi

Uma i-peptide imsulwa ngo-98%, yini u-2%?

Amaphesenti amabili okubhaliwe ancishisiwe noma asuswa izingcezwana zokulandelana.

Iyini iyunithi ye-AMU?

I-AMU iyunithi ye-micropolymerization.Lena iyunithi evamile yokulinganisa yama-peptide.

 


  • Okwedlule:
  • Olandelayo: