Kuleli phepha, kwethulwa ama-amino acid amabili ayisisekelo, i-glycine (Gly) ne-alanine (Ala).Lokhu kungenxa yokuthi bangasebenza njengama-amino acid ayisisekelo futhi ukwengeza amaqembu kuwo kungakhiqiza ezinye izinhlobo zama-amino acid.
I-Glycine inokunambitheka okumnandi okukhethekile, ngakho igama layo lesiNgisi livela kwelesiGreek glykys(elimnandi).Ukuhunyushwa kwesiShayina kwe-glycine akugcini nje ngokuthi "okumnandi", kodwa futhi kunendlela yokubiza efanayo, engabizwa ngokuthi imodeli "yokwethembeka, impumelelo nobuhle".Ngenxa yokunambitheka kwayo okumnandi, i-glycine ivame ukusetshenziswa njenge-agent yokunambitheka embonini yokudla ukuze isuse umunyu nokwandisa ubumnandi.Iketango elisemaceleni le-glycine lincane eline-athomu ye-hydrogen eyodwa kuphela.Lokho kumenza ahluke.Kuyi-amino acid eyisisekelo ngaphandle kwe-chirality.
I-Glycine emaphrotheni ibonakala ngosayizi wayo omncane kanye nokuguquguquka.Isibonelo, ukuhlanganiswa kwe-helix enezintambo ezintathu ze-collagen kukhethekile kakhulu.Kufanele kube ne-glycine eyodwa kuzo zonke izinsalela ezimbili, ngaphandle kwalokho izodala ukuthikamezeka kwesteric kakhulu.Ngokufanayo, ukuxhumana phakathi kwezizinda ezimbili zephrotheni ngokuvamile kudinga i-glycine ukuze inikeze ukuguquguquka okuvumelanayo.Kodwa-ke, uma i-glycine iguquguquka ngokwanele, ukuzinza kwayo akwanele.
I-Glycine ingenye yeziphangi ngesikhathi sokwakheka kwe-α-helix.Isizathu siwukuthi amaketanga aseceleni mancane kakhulu ukuthi angazinzisa ukuhambisana nhlobo.Ngaphezu kwalokho, i-glycine ivame ukusetshenziselwa ukulungisa izixazululo ze-buffer.Labo kini abenza i-electrophoresis bavame ukukhumbula lokho.
Igama lesiNgisi le-alanine livela kweleJalimane elithi acetaldehyde, futhi igama lesiShayina kulula ukuliqonda ngoba i-alanine iqukethe amakhabhoni amathathu futhi igama layo lamakhemikhali yi-alanine.Leli igama elilula, njengoba kuwumlingiswa we-amino acid.Iketango laseceleni le-alanine lineqembu elilodwa kuphela le-methyl futhi likhulu kancane kunele-glycine.Lapho ngidweba amafomula esakhiwo amanye ama-amino acid angu-18, ngengeza amaqembu ku-alanine.Emaphrotheni, i-alanine ifana nesitini, into evamile yokwakha eyisisekelo engangqubuzani nanoma ubani.
Iketango laseceleni le-alanine linesithiyo esincane futhi litholakala ku-α-helix, okuyi-conformation.Iphinde izinze kakhulu uma igoqwe ngo-β.Ebunjiniyela bamaprotheni, uma ufuna ukuguqula i-amino acid ngaphandle kwethagethi ethile ephrotheni, ungakwazi ukuyiguqula ibe yi-alanine, okungelula ukucekela phansi ukuhlangana okuphelele kwephrotheni.
Isikhathi sokuthumela: May-29-2023