Dulaglutide, 923950-08-7

Isibizoi-ulaglutide – isixazululo ku-PBS/ dulaglutide

Inombolo ye-CAS:923950-08-7

Inombolo Yenkampani:GT-F002

Uchungechunge: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile- I-Ala-Trp-Leu-Val-Lys-Gly-Gl y-Gly-OH

Ifomula yemolekyuli: C149H221N37O49

Isisindo se-molecule: 3314.62

I-Dulaglutide CAS NO.923950-08-7.jpg

Izinkomba zobuchwepheshe:

Ukubukeka Impushana emhlophe
Ukuhlanzeka (HPLC) bekungu-≥95.0%

I-heterozygosity eyodwa yayingaphansi kuka-2.0%

Okuqukethwe kwe-acetic acid kusuka ku-5.0% kuya ku-12.0%

Umswakama ubungu-≤10.0%

Okuqukethwe kwe-peptide bekungu-≥80.0%

Ukupakisha Nokuthumela:

Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, okunembile ku-milligram uma ucela.

Incazelo Yomkhiqizo:

I-Durraglutide iyi-agonist entsha esebenza isikhathi eside ye-GLP-1R, esuselwe ekuhlanganisweni kwe-DPP-4 inhibitory GLP-1 analogue kanye nesiqephu seketango elisindayo le-immunoglobulin ye-IgG4-Fc.Umsebenzi wayo uyafana nalowo we-GLP-1 engapheli ekubonakalisweni komtholampilo, ngesigamu sempilo yezinsuku ezi-5, futhi ingabambezela ngempumelelo imvume yezinso.I-FDA igunyaze i-dulaglutide ngomjovo ongaphansi kwesikhumba ngo-Septhemba 2014. I-European Commission igunyaze i-dulaglutide ngomjovo ongaphansi kwesikhumba e-Europe ngo-December 2014.

Isitoreji: Yiqhwa yomiswe ku -20 ℃ futhi igcinwe kude nokukhanya

Phawula: Ngezinjongo zocwaningo kuphela, hhayi ezifundweni zabantu