I-Terlipressin acetate

Inombolo yomkhiqizo: GT-D009

Igama lesiNgisi: Terlipressin acetate

Igama lesiNgisi: Terlipressin acetate

Ukulandelana: I-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Ibhuloho le-Disulfide: Cys4-Cys9)

I-CAS: 1884420-36-3

Ubumsulwa: ≥98% (HPLC)

Ifomula yemolekyuli: C52H74N16O15S2

Isisindo se-molecule: 1227.37

Ukubukeka: impushana emhlophe

Izimo zokugcina: Gcina ku -20°C, izinga lokushisa eliphansi futhi uvikelekile ekukhanyeni

Ukunyibilika: H2O: 100 mg/mL (74.21 mM; Idinga i-ultrasonic) DMSO: 100 mg/mL (74.21 mM; Idinga i-ultrasonic)

I-Terlipressin acetate

Mayelana NATHI:

I-Terlipressin, eyaziwa ngamakhemikhali ngokuthi i-triglycyl-lysine vasopressin, iyinoveli yokwenziwa kokwenziwa kwe-vasopressin esebenza isikhathi eside.Kuyi-prodrug engasebenzi futhi "ikhishwa" kancane kancane ku-lysine vasopressin esebenzayo ku-vivo ngesenzo se-aminopeptidase ukususa izinsalela ezintathu ze-glycyllyl ku-N terminus yayo.Ngakho-ke, i-terlipressin ilingana ne-reservoir ye-lysine vasopressin ekhishwa ngezinga elizinzile.