Umehluko phakathi kwamaketanga e-peptide namaketanga e-peptide

Umehluko phakathi kwamaketanga e-peptide namaketanga e-peptide yile:

1.imvelo ehlukene.

2.Izici ezihlukene.

3.inani lama-amino acid ahlukene.

Yakhiwa ama-amino acid amathathu noma ngaphezulu i-peptide yamangqamuzana i-polypeptide, isisindo sayo samangqamuzana esingaphansi kuka-10000 Da, ingadlula kulwelwesi olungenamanzi, olungaconsi nge-trichloroacetic acid ne-ammonium sulfate.Iketango le-peptide yigama lebhayoloji, elixhunywe ukuphelelwa amanzi emzimbeni kanye nokufiphala kwama-amino acid amaningi ukuze akhe izibopho ze-peptide (izibopho zamakhemikhali).

Umehluko phakathi kwamaketanga e-peptide namaketanga e-peptide

1.imvelo ehlukene.

I-Polypeptide: Inhlanganisela ye-α-amino acid exhunywe ndawonye ngamabhondi e-peptide.Kungumkhiqizo ophakathi nendawo we-proteolysis.

I-Peptide CHAIN: Wonke ama-amino acid amabili axhunywe ukwakha isibopho se-peptide, ama-amino acid amaningi axhunywe ukwakha isibopho se-peptide eningi, uchungechunge lwama-amino acid axhumene kwelinye aqukethe amabhondi amaningi e-peptide.

2. Izici ezahlukene.

Ama-Peptides: Ama-Peptides anohlu olubanzi lokuncibilika.Inkinga enkulu yokungancibiliki kwe-peptide ukwakheka kwezakhiwo zesibili."Lokhu kwenzeka kubo bonke ngaphandle kwama-peptide ayingozi kakhulu futhi kugqama kakhulu kuma-peptide anezinsalela eziningi ze-hydrophobic."

I-Peptide CHEIN: Lapho ama-amino acid amabili ejoyina ukuze akhe isibopho se-peptide, i-molecule yamanzi iyakhululwa (noma yakheka).Yileyo ndlela mangaki ama-peptide bond formation, mangaki ama-molecule amanzi azovela.Ngakho-ke mangaki amabhondi akhona ochungechungeni lwe-peptide, mangaki ama-molecule amanzi azophuma.

3.inani lama-amino acid lihlukile.

I-Polypeptide: imvamisa ukusuka ku-10 kuye kwayi-100 wama-amino acid ama-molecule afingqiwe ukuphelelwa amanzi emzimbeni.

Amaketanga e-Peptide: ama-peptide aqukethe ama-peptide amabili, ama-peptide amathathu, njll., ahlanganisa nama-peptide.