I-Amyloid β-Protein (1-6) /214550-64-8/GT Peptide/Peptide Supplier

Ulwazi oluyisisekelo:

I-PeptideName:I-Amyloid β-Protein (1-6)

Ikhathalogi No:I-GT-P005

Ukulandelana:H-Asp-Ala-Glu-Phe-Arg-His-OH

Inombolo ye-CAS:214550-64-8 

I-Molecular Formula:I-C33H47N11O11

Isisindo se-Molecular:773.80

Isigaba: Ikhathalogi peptide,I-peptide yangokwezifiso, i-polypeptide synthesis


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

II-Amyloid β-Protein (1-6) ucezu luphakanyiswe njengemodeli esebenzayo engu-2+ yokusebenzisana ukuze kuhlolwe umnikelo wezinsalela eziyinhloko ze-histidine (Ezakhe, Ezakhe kugundane nezaKhe, Zakhe, Zakhe kucezu lomuntu) ku-Ab-Cu.Izinhloso ze-oxidative ze-Amyloidβ-Amaprotheni (1-6) ayizinsalela ze-histidine ezixhumanisa nama-ion ensimbi.I-Copper ibophezela ku-Aβ ku-senile plaque yesifo i-Alzheimer's, kanye ne-Amyloidβ-Amaprotheni (1-6) abandakanyeka ekuxhumaniseni i-2+ ion yethusi.I-Copper 2+ ne-zinc 2+ iye yathinteka ku-neurotoxicity kanye nomonakalo wamahhala we-amyloid [1].I-Beta-amyloid (1-16) iwukulandelana kwe-amino acid encane kakhulu futhi ibonisa iphethini yokuxhumana ye-Cu ehlanganisa ama-histidines amathathu (His6, His13, kanye ne-His14).I-Beta-Amyloidβ-Amaprotheni (1-6) kufanele ahileleke ekubopheni insimbi [2].I-beta-amyloid yomuntu isebenzisana nama-zinc ions ngokusebenzisa isizinda sayo esibophezelayo sensimbi 1-16.Imisila ye-C yamaketanga e-polypeptide amabili egundane Aβ(1-16) i-dimer iqondiswe ngokuphambene enye nenye, okuvimbela ukuhlangana kwegundane Aβ i-dimers ibe ama-oligomers.

Imininingwane

Ukubukeka: Impushana emhlophe ukuya kokumhlophe

Ubumsulwa(HPLC):98.0%

Ukungcola Okukodwa:2.0%

Okuqukethwe kwe-Acetate(HPLC): 5.0%12.0%

Okuqukethwe Amanzi (Karl Fischer):10.0%

Okuqukethwe kwe-Peptide:80.0%

Ukupakisha Nokuthumela: Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, kunembile ku-mg njengoba kudingeka.

Unga-oda Kanjani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda ku-inthanethi.Sicela ugcwalise ifomu le-oda ku-inthanethi.

3. Nikeza igama le-peptide, Inombolo ye-CAS noma ukulandelana, ukuhlanzeka nokuguqulwa uma kudingeka, ubuningi, njll. sizohlinzeka ngekhotheshini kungakapheli amahora ama-2.

4. Ukugcinwa kwe-oda ngenkontileka yokuthengisa esayiniwe ngokufanelekile kanye ne-NDA(isivumelwano esingadalulwanga) noma isivumelwano esiyimfihlo.

5. Sizoqhubeka nokubuyekeza inqubekelaphambili ye-oda ngesikhathi.

6. Ukulethwa kwe-Peptide nge-DHL, i-Fedex noma abanye, kanye ne-HPLC, MS, COA izohlinzekwa kanye nempahla.

7. Inqubomgomo yembuyiselo izolandelwa uma kukhona ukushayisana kwekhwalithi noma isevisi yethu.

8. Isevisi yangemuva kokuthengisa: Uma amakhasimende ethu enemibuzo mayelana ne-peptide yethu ngesikhathi sokuhlolwa, sicela ukhululeke ukusithinta futhi sizoyiphendula ngokushesha.

Yonke imikhiqizo yenkampani isetshenziselwa inhloso yocwaningo lwesayensi kuphela, yona'kwenqatshelwe ukusetshenziswa ngokuqondile yinoma yimuphi umuntu emzimbeni womuntu.

FAQ:

Yiziphi izincomo uma ngiqala ukusebenzisa ama-peptide?

Uma usulungele ukusetshenziswa, landela lezi zinyathelo ezingezansi ukuze uncibilikise ama-peptide ukuze ugcine ikhwalithi yawo.

 

1, ngaphambi kokuvula ibhodlela nokukala ingxenye ye-peptide, yishise ukuze ufinyelele izinga lokushisa legumbi, futhi isikhathi sokushisa sinconywa ukuthi sibe yihora elingu-1.

2. Kala ngokushesha inani elidingekayo endaweni ehlanzekile yangaphandle.

3. Gcina ama-peptide asele efrijini ngezansi -20, engeza ama-desiccant bese uwagcina esitsheni esingangenisi umoya.

Ngihlala phesheya, futhi kuzothatha izinsuku ezimbalwa ukudiliva kanye nemvume yamasiko.Ingabe lokhu kuzoluthinta ucwaningo lwami?

Uthola ama-peptide kumaphakheji wempuphu e-lyophilized, futhi ama-peptides ngokuvamile angagcinwa endaweni yokushisa ngaphandle kokulimala.Sicela umise futhi ugcine ngokushesha ngemva kokuthola.

Yiziphi izinkinga okufanele zinakwe ohlelweni lokugcina?

I-peptide oyitholile ihlanganiswe ngempushana e-lyophilized.Ama-peptide ane-hydrophilic, futhi ukumuncwa kwamanzi kuzonciphisa ukuzinza kwe-peptide futhi kunciphise okuqukethwe kwe-peptide.Sicela unake lokhu okulandelayo: okokuqala, ngama-desiccants, agcinwe endaweni eyomile.Okwesibili, uma wathola, sicela ngokushesha ufake efrijini -20ukugcina, ukuze kugcinwe ukuzinza okukhulu.Okwesithathu, gwema ukusetshenziswa kwesiqandisi esizenzakalelayo sesiqandisi.Ukushintsha komswakama kanye nezinga lokushisa kungathinta ukuzinza kwama-peptide.Okwesine, izinga lokushisa langaphandle ngesikhathi sokuthutha akuthinti ukufaneleka kanye nekhwalithi yama-peptide.

Ngiwagcina kanjani ama-peptide afriziwe lapho ngithola umkhiqizo?

Uma usuyitholile, kufanele uyigcine ngokushesha ku -20° C noma ngaphansi.

Uma okuqukethwe kwe-peptide kungu-80%, yimuphi omunye u-20%?

Usawoti namanzi

Uma i-peptide imsulwa ngo-98%, yini u-2%?

Amaphesenti amabili okubhaliwe ancishisiwe noma asuswa izingcezwana zokulandelana.

Iyini iyunithi ye-AMU?

I-AMU iyunithi ye-micropolymerization.Lena iyunithi evamile yokulinganisa yama-peptide.


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