I-Defensin HNP-2 (umuntu)/120721-97-3 /GT Peptide/Peptide Supplier

Ulwazi oluyisisekelo:

I-PeptideName:I-Defensin HNP-2 (human)/Human Neutrophil Peptide-2, HNP-2

Ikhathalogi No:I-GT-P074

Ukulandelana:Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp- I-Ala-Phe-Cys-Cys (Amabhondi e-Disulfide phakathi kwama-Cys¹ kanye Cys²⁹/Cys³ kanye Cys¹⁸/Cyskanye Cys²⁸)

Inombolo ye-CAS:120721-97-3         

I-Molecular Formula:I-C147H217N43O37S6

Isisindo se-Molecular:3371.00

Isigaba: Ikhathalogi peptide,I-peptide yangokwezifiso, i-polypeptide synthesis


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

I-defensin HNP-2 iyi-peptide enezinto ezilwa namagciwane ekhishwa ama-polymorphonuclear leukocytes (PMN) womuntu.Yenze u-26.2% no-43.5% we-mammalian cell lysis ku-25 kanye no-100 µg/ml, ngokulandelana.Iphinde yavimbela ngokuphelele ukukhishwa kwe-Staphylococcus aureus exotoxin superantigen TSS toxin-1 (TSST-1) ekuhlanganiseni kwe-5 ng / ml futhi yavimbela ukutheleleka kwamaseli kaMcCoy nge-Chlamydia trachomatis (EB).I-defensin HNP-2 ibopha imvilophu ehlanganisiwe ye-HIV-1 i-glycoprotein gp120 kanye ne-CD4 yomuntu (Kds 8 kanye ne-15.8 nM, ngokulandelana).Iphinde ikhuthaze ukuvunyelwa kwama-vesicles ama-monolayer amakhulu (ama-LUV) akhiwe kusuka ku-1-palmitoyl-2-oleoyl-sn-glycero-3-PG (POPG, Cay-15105).

Imininingwane

Ukubukeka: Impushana emhlophe ukuya kokumhlophe

Ubumsulwa(HPLC):98.0%

Ukungcola Okukodwa:2.0%

Okuqukethwe kwe-Acetate(HPLC): 5.0%12.0%

Okuqukethwe Amanzi (Karl Fischer):10.0%

Okuqukethwe kwe-Peptide:80.0%

Ukupakisha Nokuthumela: Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, kunembile ku-mg njengoba kudingeka.

Unga-oda Kanjani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda ku-inthanethi.Sicela ugcwalise ifomu le-oda ku-inthanethi.

3. Nikeza igama le-peptide, Inombolo ye-CAS noma ukulandelana, ukuhlanzeka nokuguqulwa uma kudingeka, ubuningi, njll. sizohlinzeka ngekhotheshini kungakapheli amahora ama-2.

4. Ukugcinwa kwe-oda ngenkontileka yokuthengisa esayiniwe ngokufanelekile kanye ne-NDA(isivumelwano esingadalulwanga) noma isivumelwano esiyimfihlo.

5. Sizoqhubeka nokubuyekeza inqubekelaphambili ye-oda ngesikhathi.

6. Ukulethwa kwe-Peptide nge-DHL, i-Fedex noma abanye, kanye ne-HPLC, MS, COA izohlinzekwa kanye nempahla.

7. Inqubomgomo yembuyiselo izolandelwa uma kukhona ukushayisana kwekhwalithi noma isevisi yethu.

8. Isevisi yangemuva kokuthengisa: Uma amakhasimende ethu enemibuzo mayelana ne-peptide yethu ngesikhathi sokuhlolwa, sicela ukhululeke ukusithinta futhi sizoyiphendula ngokushesha.

Yonke imikhiqizo yenkampani isetshenziselwa inhloso yocwaningo lwesayensi kuphela, yona'kwenqatshelwe ukusetshenziswa ngokuqondile yinoma yimuphi umuntu emzimbeni womuntu.

FAQ:

Isiphi isiphetho esilungele ucwaningo lwami?

Ngokuzenzakalelayo, i-peptide iphetha ngeqembu le-amino lamahhala le-N-terminal kanye neqembu le-carboxyl lamahhala le-C-terminal.Ukulandelana kwe-peptide kuvame ukumela ukulandelana kwephrotheni kamama.Ukuze ube seduze nephrotheni kamama, ukuphela kwe-peptide kuvame ukudinga ukuvalwa, okungukuthi, i-n-terminal acetylation kanye ne-C-terminal amidation.Lokhu kuguqulwa kugwema ukwethulwa kokushaja ngokweqile, futhi kuyenza ikwazi ukuvimbela isenzo se-exonucliase, ukuze i-peptide izinze kakhudlwana.

Imaphi ama-polypeptide alungisiwe anelebula angahlanganiswa ku-peptide yesiShayina?

Inkampani yethu ihlinzeka ngezinhlobonhlobo zokulebula okuguquliwe kwe-peptide, okufana ne-acetylation, ilebula ye-biotin, ukuguqulwa kwe-phosphorylation, ukuguqulwa kwe-fluorescence, nakho kungenziwa ngezifiso ngokuya ngezidingo zakho ezikhethekile.

Ungawancibilikisa kanjani ama-polypeptides?

I-solubility ye-polypeptide incike ikakhulukazi esakhiweni sayo esiyinhloko nesesibili, imvelo yelebula yokuguqulwa, uhlobo lwe-solvent kanye nokugxila kokugcina.Uma i-peptide ingancibiliki emanzini, i-ultrasound ingasiza ukuyihlakaza.Nge-peptide eyisisekelo, kunconywa ukuba ichithe i-acetic acid engu-10%;Kuma-peptide ane-acidic, kunconywa ukuchithwa ngo-10% NH4HCO3.Izinyibilikisi ze-Organic nazo zingangezwa kuma-polypeptides angancibiliki.I-peptide incibilika enanini elincane le-solvent ephilayo (isb, i-DMSO, i-DMF, i-isopropyl alcohol, i-methanol, njll.).Kutuswa kakhulu ukuthi i-peptide incibilikiswe ku-solvent ye-organic kuqala bese yengezwa kancane kancane emanzini noma kwesinye isilondolozi kuze kube yilapho kugxiliswa okufiswayo.

Yiziphi izimo ezingcono kakhulu zokulondoloza?Iqine kangakanani i-peptide?

Ngemuva kwe-lyophilized, i-polypeptide ingenza i-fluff noma i-flocculant powder, engagwema ukuwohloka ngaphambi kwesikhathi kwe-polypeptide.Izimo zokugcina ezinconyiwe: a.-20indawo yokugcina noma eyomile b.Zama ukugwema ukuncibilika okuphindaphindiwe c.Zama ukugwema ukugcinwa esimweni sesixazululo (impushana eqandisiwe ingagcinwa emaphaketheni ahlukene ukuze kube lula ukuyisebenzisa) d.Uma kufanele igcinwe kwisisombululo, kunconywa ukuthi ichithe ama-peptide emanzini oyinyumba ngaphansi kwezimo ezibuthakathaka ze-asidi futhi igcinwe ku -20..

Ithuthwa kanjani i-peptide yami?Imiphi imibiko yokuhlola enikeziwe?

Wonke ama-polypeptide omisiwe afriziwe ngokuvamile agcinwa ezitsheni ezikhethekile ezingu-2 ml noma 10ml ezinedatha yokuhlaziya yoqobo kanye nemibiko yokuhlanganisa equkethe ulwazi olubalulekile njengokulandelana, isisindo samangqamuzana, ukuhlanzeka, isisindo, kanye nenombolo ye-polypeptide.

Siyini isisindo esiphelele?Kuyini okuqukethwe kwe-peptide?

Ngemuva kokuthi i-lyophilized peptide ngokuvamile i-fluffy futhi ifana ne-fluff, ingase iqukathe amanani amancane wamanzi, izinyibilikisi ezikhangisiwe nosawoti ngenxa yezimpawu ze-peptide ngokwayo.Lokhu akusho ukuthi ukuhlanzeka kwe-peptide akwanele, kodwa ukuthi okuqukethwe kwangempela kwe-peptide kuncipha ngo-10% kuya ku-30%.Isisindo esiphelele se-peptide yisisindo sangempela se-peptide khipha amanzi nama-ion ane-protonated.Ukuze uqinisekise ukugcwala kwe-peptide, izinto ezingezona i-peptide zidinga ukususwa ku-peptide engahluziwe.

Ingahlanzeka kangakanani i-peptide?

Inkampani yethu ingahlinzeka ngamazinga ahlukene okuhlanzeka ukuze amakhasimende akhethe kuwo, kusukela kokungcolile kuya > kokuhlanzeka okungu-99.9%.Ngokwezidingo zamakhasimende singanikeza ubumsulwa > 99.9% polypeptide ultra-pure.


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