Degarelix /214766-78-6/GT Peptide/Peptide Supplier

Incazelo

I-Degarix (Fermonger ®) isizukulwane sakamuva sabaphikisi be-GnRH.Ihlanganisa i-p-urophenylalanine endaweni yesi-5 neyesi-6 ye-molecule yayo.Ukuguqulwa kwesakhiwo samakhemikhali kuvumela umuthi ukwandisa isikhathi sesenzo ngenkathi ugwema ukuzwela okubangelwa ukukhululwa kwe-histamine.Ukusebenza komtholampilo, ukuphepha kanye nokusetshenziswa kwesikhathi eside kwe-degarelix kuqinisekisiwe ezivivinyweni eziningi zomtholampilo.Degarelixungumphikisi osetshenziswa kakhulu we-GnRH ngaphambi kwe-Chemicalbook.Ekwelapheni umdlavuza we-prostate othuthukisiwe nge-bone metastasis, i-degarelix nayo ikhombisa ukuphakama okuhle.Ucwaningo luye lwabonisa ukuthi iziguli ezine-bone metastasis yomdlavuza we-prostate ezilashwa nge-degarelix unyaka ongu-1 zinganciphisa kakhulu i-plasma alkaline phosphatase (S-ALP) uma kuqhathaniswa nokwelashwa kwe-agonist ye-GnRH, futhi ukwanda kwe-S-ALP kuvame ukuhlotshaniswa ne-bone metastasis.

Imininingwane

Ukubukeka: Impushana emhlophe ukuya kokumhlophe

Ubumsulwa(HPLC):≥98.0%

Ukungcola Okukodwa:≤2.0%

Okuqukethwe kwe-Acetate(HPLC): 5.0%～12.0%

Okuqukethwe Amanzi (Karl Fischer):≤10.0%

Okuqukethwe kwe-Peptide:≥80.0%

Ukupakisha Nokuthumela: Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, kunembile ku-mg njengoba kudingeka.

Unga-oda Kanjani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda ku-inthanethi.Sicela ugcwalise ifomu le-oda ku-inthanethi.

3. Nikeza igama le-peptide, Inombolo ye-CAS noma ukulandelana, ukuhlanzeka nokuguqulwa uma kudingeka, ubuningi, njll. sizohlinzeka ngekhotheshini kungakapheli amahora ama-2.

4. Ukugcinwa kwe-oda ngenkontileka yokuthengisa esayiniwe ngokufanelekile kanye ne-NDA(isivumelwano esingadalulwanga) noma isivumelwano esiyimfihlo.

5. Sizoqhubeka nokubuyekeza inqubekelaphambili ye-oda ngesikhathi.

6. Ukulethwa kwe-Peptide nge-DHL, i-Fedex noma abanye, kanye ne-HPLC, MS, COA izohlinzekwa kanye nempahla.

7. Inqubomgomo yembuyiselo izolandelwa uma kukhona ukushayisana kwekhwalithi noma isevisi yethu.

8. Isevisi yangemuva kokuthengisa: Uma amakhasimende ethu enemibuzo mayelana ne-peptide yethu ngesikhathi sokuhlolwa, sicela ukhululeke ukusithinta futhi sizoyiphendula ngokushesha.

Yonke imikhiqizo yenkampani isetshenziselwa inhloso yocwaningo lwesayensi kuphela, yona'kwenqatshelwe ukusetshenziswa ngokuqondile yinoma yimuphi umuntu emzimbeni womuntu.

FAQ:

Isiphi isiphetho esilungele ucwaningo lwami?

Ngokuzenzakalelayo, i-peptide iphetha ngeqembu le-amino lamahhala le-N-terminal kanye neqembu le-carboxyl lamahhala le-C-terminal.Ukulandelana kwe-peptide kuvame ukumela ukulandelana kwephrotheni kamama.Ukuze ube seduze nephrotheni kamama, ukuphela kwe-peptide kuvame ukudinga ukuvalwa, okungukuthi, i-n-terminal acetylation kanye ne-C-terminal amidation.Lokhu kuguqulwa kugwema ukwethulwa kokushaja ngokweqile, futhi kuyenza ikwazi ukuvimbela isenzo se-exonucliase, ukuze i-peptide izinze kakhudlwana.

Imaphi ama-polypeptide alungisiwe anelebula angahlanganiswa ku-peptide yesiShayina?

Inkampani yethu ihlinzeka ngezinhlobonhlobo zokulebula okuguquliwe kwe-peptide, okufana ne-acetylation, ilebula ye-biotin, ukuguqulwa kwe-phosphorylation, ukuguqulwa kwe-fluorescence, nakho kungenziwa ngezifiso ngokuya ngezidingo zakho ezikhethekile.

Ungawancibilikisa kanjani ama-polypeptides?

I-solubility ye-polypeptide incike ikakhulukazi esakhiweni sayo esiyinhloko nesesibili, imvelo yelebula yokuguqulwa, uhlobo lwe-solvent kanye nokugxila kokugcina.Uma i-peptide ingancibiliki emanzini, i-ultrasound ingasiza ukuyihlakaza.Nge-peptide eyisisekelo, kunconywa ukuba ichithe i-acetic acid engu-10%;Kuma-peptide ane-acidic, kunconywa ukuchithwa ngo-10% NH4HCO3.Izinyibilikisi ze-Organic nazo zingangezwa kuma-polypeptides angancibiliki.I-peptide incibilika enanini elincane le-solvent ephilayo (isb, i-DMSO, i-DMF, i-isopropyl alcohol, i-methanol, njll.).Kutuswa kakhulu ukuthi i-peptide incibilikiswe ku-solvent ye-organic kuqala bese yengezwa kancane kancane emanzini noma kwesinye isilondolozi kuze kube yilapho kugxiliswa okufiswayo.

Yiziphi izimo ezingcono kakhulu zokulondoloza?Iqine kangakanani i-peptide?

Ngemuva kwe-lyophilized, i-polypeptide ingenza i-fluff noma i-flocculant powder, engagwema ukuwohloka ngaphambi kwesikhathi kwe-polypeptide.Izimo zokugcina ezinconyiwe: a.-20℃indawo yokugcina noma eyomile b.Zama ukugwema ukuncibilika okuphindaphindiwe c.Zama ukugwema ukugcinwa esimweni sesixazululo (impushana eqandisiwe ingagcinwa emaphaketheni ahlukene ukuze kube lula ukuyisebenzisa) d.Uma kufanele igcinwe kwisisombululo, kunconywa ukuthi ichithe ama-peptide emanzini oyinyumba ngaphansi kwezimo ezibuthakathaka ze-asidi futhi igcinwe ku -20.℃.

Ithuthwa kanjani i-peptide yami?Imiphi imibiko yokuhlola enikeziwe?

Wonke ama-polypeptide omisiwe afriziwe ngokuvamile agcinwa ezitsheni ezikhethekile ezingu-2 ml noma 10ml ezinedatha yokuhlaziya yoqobo kanye nemibiko yokuhlanganisa equkethe ulwazi olubalulekile njengokulandelana, isisindo samangqamuzana, ukuhlanzeka, isisindo, kanye nenombolo ye-polypeptide.

Siyini isisindo esiphelele?Kuyini okuqukethwe kwe-peptide?

Ngemuva kokuthi i-lyophilized peptide ngokuvamile i-fluffy futhi ifana ne-fluff, ingase iqukathe amanani amancane wamanzi, izinyibilikisi ezikhangisiwe nosawoti ngenxa yezimpawu ze-peptide ngokwayo.Lokhu akusho ukuthi ukuhlanzeka kwe-peptide akwanele, kodwa ukuthi okuqukethwe kwangempela kwe-peptide kuncipha ngo-10% kuya ku-30%.Isisindo esiphelele se-peptide yisisindo sangempela se-peptide khipha amanzi nama-ion ane-protonated.Ukuze uqinisekise ukugcwala kwe-peptide, izinto ezingezona i-peptide zidinga ukususwa ku-peptide engahluziwe.

Ingahlanzeka kangakanani i-peptide?

Inkampani yethu ingahlinzeka ngamazinga ahlukene okuhlanzeka ukuze amakhasimende akhethe kuwo, kusukela kokungcolile kuya > kokuhlanzeka okungu-99.9%.Ngokwezidingo zamakhasimende singanikeza ubumsulwa > 99.9% polypeptide ultra-pure.