I-Myristoyl tripeptide-1/748816-12-8/GT Peptide/Peptide Supplier

Incazelo

I-Myristic tripeptide ivimbela ukulotshwa nokuhumusha kofuzo lwe-Matrix Metalloproteinase 1 (MMP-1) futhi ithuthukisa ukwakheka kohlobo I-procollagen.Ukuvinjelwa kwenkulumo ye-melanin gene, synthesis melanin kanye nomsebenzi we-tyrosinase.

Imininingwane

Ukubukeka: Impushana emhlophe ukuya kokumhlophe

Ubumsulwa(HPLC):≥98.0%

Ukungcola Okukodwa:≤2.0%

Okuqukethwe kwe-Acetate(HPLC): 5.0%～12.0%

Okuqukethwe Amanzi (Karl Fischer):≤10.0%

Okuqukethwe kwe-Peptide:≥80.0%

Ukupakisha Nokuthumela: Izinga lokushisa eliphansi, ukupakisha kwe-vacuum, kunembile ku-mg njengoba kudingeka.

Unga-oda Kanjani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda ku-inthanethi.Sicela ugcwalise ifomu le-oda ku-inthanethi.

3. Nikeza igama le-peptide, Inombolo ye-CAS noma ukulandelana, ukuhlanzeka nokuguqulwa uma kudingeka, ubuningi, njll. sizohlinzeka ngekhotheshini kungakapheli amahora ama-2.

4. Ukugcinwa kwe-oda ngenkontileka yokuthengisa esayiniwe ngokufanelekile kanye ne-NDA(isivumelwano esingadalulwanga) noma isivumelwano esiyimfihlo.

5. Sizoqhubeka nokubuyekeza inqubekelaphambili ye-oda ngesikhathi.

6. Ukulethwa kwe-Peptide nge-DHL, i-Fedex noma abanye, kanye ne-HPLC, MS, COA izohlinzekwa kanye nempahla.

7. Inqubomgomo yembuyiselo izolandelwa uma kukhona ukushayisana kwekhwalithi noma isevisi yethu.

8. Isevisi yangemuva kokuthengisa: Uma amakhasimende ethu enemibuzo mayelana ne-peptide yethu ngesikhathi sokuhlolwa, sicela ukhululeke ukusithinta futhi sizoyiphendula ngokushesha.

Yonke imikhiqizo yenkampani isetshenziselwa inhloso yocwaningo lwesayensi kuphela, yona'kwenqatshelwe ukusetshenziswa ngokuqondile yinoma yimuphi umuntu emzimbeni womuntu.

FAQ

Yimiphi imikhawulo ngobude bama-peptide okwenziwa?

I-polypeptide ehlanganiswe yinkampani yethu ingama-amino acid ayi-6 ~ 50 ubude.Izinqubo ezijwayelekile zokuhlanganisa isigaba esiqinile ngokuvamile zikhiqiza ama-peptide angu-6 kuye kwangama-50 amino acid.

Zichazwa kanjani iziqongo ze-P+Na ne-P+K ku-MALDI(MS)?

Iziqongo i-Na ne-K zivame ukubonakala eMALDI, kanti i-sodium ne-potassium ziphuma emanzini ancibilikayo.Ngisho namanzi acwengekile nahlanganisiwe angaqukatha amanani e-sodium ne-potassium ion angakwazi ukususwa ngokuphelele.Futhi zi-ionize futhi zibophe eqenjini le-carboxyl lamahhala le-peptide ngesikhathi se-mass spectrometry.Ngenxa yokuthi alukho uhlelo lokuhlanza lokususa ama-ion e-sodium ne-potassium emanzini, kwesinye isikhathi akunakugwemeka ukuthi iziqongo zesodium ne-potassium zivele kumephu ye-MALDI MS.

Sicela uchaze isu lakho lokuhlanza

Ama-peptide ahlanganiswe yinkampani yethu ahlanzwa nge-HPLC yesigaba esihlehlisiwe esine-TFA ne-pH 2 yengezwe kuzo zombili izigaba zamaselula.Isigaba A singu-0.1% TFA emanzini ahlanzekile kakhulu, futhi isigaba B singu-0.1% TFA ku-ACN, i-pH 2. Isampula ingancibilika ngokuqondile esigabeni A, noma incibilike ku-A inani elincane lesigaba B futhi ihlanjululwe ngesigaba esingu-A.Ngezinye izikhathi kungase kudingeke ukuncibilikisa ama-peptide e-hydrophobic ngezincibilikisi ezinamandla njenge-formic acid noma i-acetic acid, kuye ngokulandelana kwe-peptide.Ku-pH 6.8, ngokuvamile kunzima ukuncibilikisa kanye nokuhlanza i-peptide, ngakho-ke sivamise ukuncibilikisa i-peptide kuqala bese sisebenzisa izigaba ezimbili zamaselula ukuze sithole i-gradient.Isixazululo sebhafa ku-pH 6.8 sasingu-10 mM ammonium acetate emanzini ahlanzekile kakhulu (isigaba seselula A), i-ACN ehlanzekile (isigaba B seselula).Izingxenye ezihlukene zaqoqwa futhi zahlonzwa yi-MADLI-TOF MS.Ubumsulwa buhlaziywe yi-HPLC yesigaba esibuyiselwe emuva.Khona-ke, ama-peptide okuhlosiwe ayenziwe nge-lyophilized, futhi ama-peptide a-lyophilized ahlanganiswa abe izitsha ezincane.

Uyiqapha kanjani imikhiqizo yakho?

Wonke ama-peptide okwenziwa ahlaziywa yi-HPLC ne-MS, ngaphandle kwe-MALDIMS.Njengoba ama-peptide enziwe i-ionized ngokulandelana kwawo kuma-spectrometer amaningi ahlukene, amasu e-HPLC-MS angasetshenziswa ukuhlaziya lezo ziqongo ze-ionization ku-HPLC.Imishini yethu yobuchwepheshe [MALDI-MS, HPLC-(ESI)MS (ion trap and tetrode array)] inikeza isiqinisekiso esinokwethenjelwa sokuhlaziya.

Ingabe ukunyibilika kwe-peptide kuhlobene nekhwalithi ye-peptide?

Ama-peptides okwenziwa awancibiliki kahle, ama-peptides anenkinga, akunjalo?

IMP: Kunzima ukubikezela kahle ukuthi i-peptide inyibilika kanjani nokuthi siyini isincibilikisi esifanele.Akulona iqiniso ukuthi kunenkinga nge-peptide synthesis uma kunzima ukuyihlakaza.

Uwagcina kanjani ama-peptides kusisombululo?

Uma kufanele ugcine ama-peptide akho oketshezini, sebenzisa isigcina magciwane ku-PH 5-6 futhi ugcine ku- -20℃ukunweba impilo yama-peptide akho esixazululo.

Ngabe ama-peptide ahlala isikhathi esingakanani esixazululo?

Kungcono ukungagcini ama-peptide asele esixazululweni.Impilo yeshalofu ye-polypeptides esixazululweni ilinganiselwe kakhulu, ikakhulukazi lezo ezine-cysteine, i-methionine, i-tryptophan, i-asparagic acid, i-glutamic acid, ne-N-terminal glutamic acid ngokulandelana.Ngokuvamile, khipha inani elidingekayo lokusetshenziswa, lonke iqhwa lomisiwe ukuze ligcinwe isikhathi eside.